Cytokines, Inflammation, and Pain

Cytokines and pain.

BACKGROUND AND OBJECTIVES Cytokines are necessary for the inflammatory response, favoring proper wound healing. However, exaggerated proinflammatory cytokine production can manifest systemically as hemodynamic instability or metabolic derangements. The objective of this review was to describe the effects of cytokines in pain. CONTENTS This article reviews the effects of cytokines in pain. In ...

Cells and Cytokines in Lung Inflammation

The cellular and cytokine network that regulates the human IgE synthesis has recently been clarified. In contrast to intracellular bacteria, that induce the activation of helper T cells producing IFN-,, but not IL-4 (WH cells), allergens and helminths preferentially activate helper T cells that produce IL-4, but not IFN-, (TH cells). TH cells provide the B cells with both signals (T/B cell cont...

Cytokines in immunity and inflammation group

Renal failure, anaemia, cytokines and inflammation.

Sir, We have read with interest the editorial comment by Ba  rany w1x on the negative effects of in¯ammation on erythropoiesis, and the importance of this condition as cause of resistance to erythropoietin (Epo) in dialysis patients. In this context, we would like to highlight the relevance of in¯ammation as a potential factor contributing to anaemia in patients with advanced renal failure in ...

Cytokines in acute and chronic inflammation.

Inflammation is mediated by a variety of soluble factors, including a group of secreted polypeptides known as cytokines. Inflammatory cytokines can be divided into two groups: those involved in acute inflammation and those responsible for chronic inflammation. This review describes the role played in acute inflammation by IL-1, TNF-alpha, IL-6, IL-11, IL-8 and other chemokines, G-CSF, and GM-CS...